A novel interaction between N-myristoylation and the 26S proteasome during cell morphogenesis.

Abstract excerpt

N-myristoylation is a protein lipidation event in which myristate is covalently linked to the N-terminal glycine of target proteins. In Aspergillus nidulans, the N-myristoylation deficient swoF1 mutant was previously shown to lose cell polarity during the early morphogenic event of germ tube emergence. To further investigate this defect, we mutagenized swoF1 and recovered six partial suppressors designated ssf...

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