Article
A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data.
Bioinformatics (Oxford, England) - 15 Jan 2007
Yosef Nir, Yakhini Zohar, Tsalenko Anya, Kristensen Vessela, Børresen-Dale Anne-Lise, Ruppin Eytan, Sharan Roded
Abstract excerpt
MOTIVATION: Large-scale association studies, investigating the genetic determinants of a phenotype of interest, are producing increasing amounts of genomic variation data on human cohorts. A fundamental challenge in these studies is the detection of genotypic patterns that discriminate individuals exhibiting the phenotype under study from individuals that do not possess it. The difficulty stems from the large...
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