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Article

Early Aldosterone-Regulated Genes in Cardiomyocytes: Clues to Cardiac Remodeling?

19 Jan 2007

Abstract excerpt

Recent clinical studies demonstrated beneficial effects of mineralocorticoid receptor (MR) antagonists in patients with heart failure and other cardiovascular diseases. However, the underlying molecular mechanisms are poorly understood, and the genes that mediate direct effects of aldosterone in the cardiovascular system are yet to be identified. The goal of this study was to identify genes that are directly...

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Share to Cardiovascular, Neuropeptides, and Oxidative Stress Research
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Identifiers

PMID: 17234708
DOI: 10.1210/en.2006-1438

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