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Article

The GacS sensor kinase controls phenotypic reversion of small colony variants isolated from biofilms of Pseudomonas aeruginosa PA14.

FEMS microbiology ecology - 1 Jan 2007

Davies James A, Harrison Joe J, Marques Lyriam L R, Foglia Ginevra R, Stremick Carol A, Storey Douglas G, Turner Raymond J, Olson Merle E, Ceri Howard

Abstract excerpt

The GacS/GacA two-component regulatory system in pseudomonads regulates genes involved in virulence, secondary metabolism and biofilm formation. Despite these regulatory functions, some Pseudomonas species are prone to spontaneous inactivating mutations in gacA and gacS. A gacS(-) strain of Pseudomonas aeruginosa PA14 was constructed to study the physiological role of this sensor histidine kinase. This...

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PMID: 17233744
DOI: 10.1111/j.1574-6941.2006.00196.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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