Article
Molecular nature of spontaneous modifications in gacS which cause colony phase variation in Pseudomonas sp. strain PCL1171.
Journal of bacteriology - 1 Jan 2005
van den Broek Daan, Chin-A-Woeng Thomas F C, Bloemberg Guido V, Lugtenberg Ben J J
Abstract excerpt
Pseudomonas sp. strain PCL1171 displays colony phase variation between opaque phase I and translucent phase II colonies, thereby regulating the production of secondary metabolites and exoenzymes. Complementation and sequence analysis of 26 phase II mutants and of 13 wild-type phase II sectors growing out of phase I colonies showed that in all these cases the phase II phenotype is caused by spontaneous mutations...
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