Article
Pseudomonas aeruginosa GacA, a factor in multihost virulence, is also essential for biofilm formation.
Molecular microbiology - 1 Jun 2001
Parkins M D, Ceri H, Storey D G
Abstract excerpt
We have investigated a potential role for GacA, the response regulator of the GacA/GacS two-component regulatory system, in Pseudomonas aeruginosa biofilm formation. When gacA was disrupted in strain PA14, a 10-fold reduction in biofilm formation capacity resulted relative to wild-type PA14. However, no significant difference was observed in the planktonic growth rate of PA14 gacA(-). Providing gacA in trans on...
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