Article
Is FLT3 internal tandem duplication significant indicator for allogeneic transplantation in acute myeloid leukemia? An analysis of patients from the Czech Acute Leukemia Clinical Register (ALERT).
Neoplasma - 1 Jan 2007
Doubek M, Muzík J, Szotkowski T, Koza V, Cetkovský P, Kozák T, Zák P, Voglová J, Struncová S, Dusek L, Indrák K
Abstract excerpt
To assess the prognostic relevance of activating mutations of FLT3 gene on outcome of allogeneic transplantations in AML patients, we performed an analysis of all patients with FLT3 mutations registered in the Czech Acute Leukemia Clinical Register (ALERT) from 2003 till the end of 2005. Within the mentioned period 170 patients with AML of median age 56 years (23-77) were investigated for FLT3 mutation, within...
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