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Article

Adaptive response to DNA and chromosomal damage induced by X-rays in human blood lymphocytes

18 Jan 2007

Abstract excerpt

Nucleoid sedimentation, single-cell gel electrophoresis (comet assay) and premature chromosome condensation (PCC) technique were utilized to estimate the involvement of DNA strand breaks and chromosomal damage in radio-adaptive response of stimulated human lymphocytes. Conditioning of cells with 0.02 Gy X-rays rendered them more resistant to single- and double-strand DNA breaks produced by 1 Gy challenging...

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PMID: 17229819
DOI: 10.1093/mutage/gel061

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