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Article

Notch signal organizes the Drosophila olfactory circuitry by diversifying the sensory neuronal lineages.

Nature neuroscience - 1 Feb 2007

Endo Keita, Aoki Tomoko, Yoda Yuka, Kimura Ken-ichi, Hama Chihiro

Abstract excerpt

An essential feature of the organization and function of the vertebrate and insect olfactory systems is the generation of a variety of olfactory receptor neurons (ORNs) that have different specificities in regard to both odorant receptor expression and axonal targeting. Yet the underlying mechanisms that generate this neuronal diversity remain elusive. Here we demonstrate that the Notch signal is involved in the...

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PMID: 17220884
DOI: 10.1038/nn1832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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