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Article

Genotyping and segregation analyses indicate the presence of only two functional MIC genes in rhesus macaques.

Immunogenetics - 1 Mar 2007

Averdam Anne, Seelke Sandra, Grützner Immanuel, Rosner Cornelia, Roos Christian, Westphal Nico, Stahl-Hennig Christiane, Muppala Vijayakumar, Schrod Annette, Sauermann Ulrike, Dressel Ralf, Walter Lutz

Abstract excerpt

MIC molecules are stress-inducible ligands of the activating receptor NKG2D, which is expressed on natural killer cells and subsets of T lymphocytes. In rhesus macaques (Macaca mulatta), three different MIC sequences (MIC1, MIC2, MIC3) have been described that are closely related to but, according to phylogenetic analysis, do not represent orthologues of the human MICA and MICB genes. Although a single haplotype...

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Identifiers

PMID: 17216437
DOI: 10.1007/s00251-006-0187-1

Genes

MICA
MICB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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