Article
Identification of genes related to Parkinson's disease using expressed sequence tags.
DNA research : an international journal for rapid publication of reports on genes and genomes - 31 Dec 2006
Kim Jeong-Min, Lee Kyu-Hwa, Jeon Yeo-Jin, Oh Jung-Hwa, Jeong So-Young, Song In-Sung, Kim Jin-Man, Lee Dong-Seok, Kim Nam-Soon
Abstract excerpt
In a search for novel target genes related to Parkinson's disease (PD), two full-length cDNA libraries were constructed from a human normal substantia nigra (SN) and a PD patient's SN. An analysis of the gene expression profiles between them was done using the expressed sequence tags (ESTs) frequency. Data for the differently expressed genes were verified by quantitative real-time RT-PCR, immunohistochemical...
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