Article
Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern China.
Cancer causes & control : CCC - 1 Mar 2007
Wang Yimin, Guo Wei, He Yutong, Chen Zhifeng, Wen Denggui, Zhang Xiufeng, Wang Na, Li Yan, Ge Hui, Zhang Jianhui
Abstract excerpt
OBJECTIVE: To assess the association between the C to T transition in the methylenetetrahydro folate reductase gene (MTHFR C677T) and the C to T transition in the serine hydroxymethyltransferase ( 1 )gene (SHMT ( 1 ) C1420T) and the increased risk of carcinogenesis of esophageal squamous cell carcinoma (ESCC) and gastric cardia adenocarcinoma (GCA) in a population of high incident region of Northern China....
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