Article
BoLA class I allele diversity and polymorphism in a herd of cattle.
Immunogenetics - 1 Feb 2007
Babiuk Shawn, Horseman Benjamin, Zhang Chenhong, Bickis Mik, Kusalik Anthony, Schook Lawrence B, Abrahamsen Mitchell S, Pontarollo Reno
Abstract excerpt
Major histocompatibility complex class I genes are among the most polymorphic genes characterized. The high level of polymorphism is essential for generating host immune responses. In humans, three distinct genomic loci encode human leukocyte antigen (HLA) class I genes, allowing individuals to express up to six different HLA class I molecules. In cattle, the number of distinct genomic loci are currently at least...
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