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Article

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

1 Dec 1991

Abstract excerpt

Recurring chromosomal translocations involving chromosome 11, band q23, have been observed in acute lymphoid leukemias and especially in acute myeloid leukemias. We recently showed that breakpoints in four 11q23 translocations, t(4;11)(q21;q23), t(6;11)(q27;q23), t(9;11)(p22;q23), and t(11;19)(q23;p13.3), were contained within a yeast artificial chromosome clone bearing the CD3D and CD3G gene loci. We have...

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Identifiers

PMID: 1720549
DOI: 10.1073/pnas.88.23.10735

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Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.PMID 1720549Read ↗

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