A B cell line from a patient with pure red cell aplasia produces an immunoglobulin that suppresses erythropoiesis.

doi:10.1016/s0090-1229(06)80004-8

Back to search

Article

A B cell line from a patient with pure red cell aplasia produces an immunoglobulin that suppresses erythropoiesis.

Clinical immunology and immunopathology - 1 Oct 1991

Nagasawa M, Okawa H, Yata J

Abstract excerpt

A 4-year-old boy with pure red cell aplasia was investigated. Immunophenotypic analysis of peripheral blood lymphocytes revealed a marked increase of CD20+ cells, which fell from 25.9% in the active stage to 9.7% in remission. The plasma contained a suppressive activity against CFU-e and BFU-e fo...

Topics

B-Lymphocytes
Cell Line
Child, Preschool
Erythropoiesis
Humans
Immunoglobulins
Lymphocyte Subsets
Male
Phenotype
Red-Cell Aplasia, Pure
gamma-Globulins

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.