Article
HLA mismatching within or outside of cross-reactive groups (CREGs) is associated with similar outcomes after unrelated hematopoietic stem cell transplantation.
Blood - 1 May 2007
Wade Judith A, Hurley Carolyn Katovich, Takemoto Steven K, Thompson John, Davies Stella M, Fuller Thomas C, Rodey Glenn, Confer Dennis L, Noreen Harriet, Haagenson Michael, Kan Fangyu, Klein John, Eapen Mary, Spellman Stephen, Kollman Craig
Abstract excerpt
The National Marrow Donor Program maintains a registry of volunteer donors for patients in need of a hematopoietic stem cell transplantation. Strategies for selecting a partially HLA-mismatched donor vary when a full match cannot be identified. Some transplantation centers limit the selection of mismatched donors to those sharing mismatched antigens within HLA-A and HLA-B cross-reactive groups (CREGs). To assess...
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