Article
Microarray-Based Identification of Tenascin C and Tenascin XB , Genes Possibly Involved in Tumorigenesis Associated with Neurofibromatosis Type 1
4 Jan 2007
Abstract excerpt
PURPOSE: Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder with a complex variety of clinical manifestations. The hallmark of NF1 is the onset of heterogeneous (dermal or plexiform) benign neurofibromas. Plexiform neurofibromas can give rise to malignant peripheral nerve sheath tumors, which are resistant to conventional therapies. EXPERIMENTAL DESIGN: To identify new signaling pathways involved in...
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