Article
Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor
4 Jan 2007
Abstract excerpt
Lymphatic vessels develop from specialized venous endothelial cells. Using knockout mice, we found that fasting-induced adipose factor (Fiaf) is required for functional partitioning of postnatal intestinal lymphatic and blood vessels. In wild-type animals, levels of intestinal Fiaf expression rise during the first postnatal day and peak at day 2, which coincides with the onset of the lymphatico-venous...
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