Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets.

The American journal of pathology - 1 Apr 2012

Truman Lucy A, Bentley Kevin L, Smith Elenoe C, Massaro Stephanie A, Gonzalez David G, Haberman Ann M, Hill Myriam, Jones Dennis, Min Wang, Krause Diane S, Ruddle Nancy H

Abstract excerpt

Lymphatic vessels (LVs) are important structures for antigen presentation, for lipid metabolism, and as conduits for tumor metastases, but they have been difficult to visualize in vivo. Prox1 is a transcription factor that is necessary for lymphangiogenesis in ontogeny and the maintenance of LVs. To visualize LVs in the lymph node of a living mouse in real time, we made the ProxTom transgenic mouse in a C57BL/6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Medulla
Share to Blood Platelets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Luminescent Proteins

Share to Lymph Nodes

Share to Lymphatic Vessels

Share to Megakaryocytes

Share to Red Fluorescent Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 22310467
DOI: 10.1016/j.ajpath.2011.12.026
PMCID: PMC3349900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets.PMID 22310467Read ↗

A Transgenic Prox1-Cre-tdTomato Reporter Mouse for Lymphatic Vessel ResearchSemantic proximity Read ↗

Efficient Assessment of Developmental, Surgical and Pathological Lymphangiogenesis Using a Lymphatic Reporter Mouse and Its Embryonic Stem CellsSemantic proximity Read ↗

Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic <i>Prox1</i> promoter-directed mOrange2 reporter mouseSemantic proximity Read ↗

Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouseSemantic proximity Read ↗

Mouse brain lymphatic vesselsSemantic proximity Read ↗

Development and Characterization of A Novel Prox1-EGFP Lymphatic and Schlemm’s Canal Reporter RatSemantic proximity Read ↗

Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and functionSemantic proximity Read ↗

Coordinated lymphangiogenesis is critical in lymph node development and maturationSemantic proximity Read ↗

Nanobody immunolabelling and three-dimensional imaging reveals spatially restricted LYVE1 expression by kidney lymphatic vessels in miceSemantic proximity Read ↗

<i>lyve1</i> expression reveals novel lymphatic vessels and new mechanisms for lymphatic vessel development in zebrafishSemantic proximity Read ↗

Genetic lineage tracing identifies intermediate mesoderm as a novel contributor to mammalian kidney lymphaticsSemantic proximity Read ↗

Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.