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Article

RNA recognition mechanism of the minimal active domain of the human immunodeficiency virus type-2 nucleocapsid protein.

Journal of biochemistry - 1 Feb 2007

Matsui Takashi, Kodera Yoshio, Endoh Hiroshi, Miyauchi Emi, Komatsu Hiroyoshi, Sato Kazuki, Tanaka Takeshi, Kohno Toshiyuki, Maeda Tadakazu

Abstract excerpt

NCp8 of HIV-2 contains two CCHC-type zinc fingers connected by a linker, and is involved in many critical steps of the virus life cycle. It was previously shown that the first zinc finger flanked by the linker is the minimal active domain for specific binding to viral RNA. In our previous study, we determined the three-dimensional structure of NCp8-f1, including the minimal active domain, and found that a...

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Source

Identifiers

PMID: 17202191
DOI: 10.1093/jb/mvm037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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