Article
Risk Factors for Ovarian Cancer by BRCA Status: A Collaborative Case-Only Analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 3 Apr 2024
Gersekowski Kate, Na Renhua, Alsop Kathryn, Delahunty Rachel, Goode Ellen L, Cunningham Julie M, Winham Stacey J, Pharoah Paul D P, Song Honglin, Webb Penelope M
Abstract excerpt
BACKGROUND: Women with an inherited pathogenic variant in BRCA1 or BRCA2 have a greatly increased risk of developing ovarian cancer, but the importance of behavioral factors is less clear. We used a case-only design to compare the magnitude of associations with established reproductive, hormonal, and lifestyle risk factors between BRCA mutation carriers and noncarriers. METHODS: We pooled data from five studies...
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