Effect of glutathione S-transferase polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: results from the Roxbury lupus project.

doi:10.1002/art.22308

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Article

Effect of glutathione S-transferase polymorphisms and proximity to hazardous waste sites on time to systemic lupus erythematosus diagnosis: results from the Roxbury lupus project.

Arthritis and rheumatism - 1 Jan 2007

Karlson Elizabeth W, Watts Julie, Signorovitch James, Bonetti Marco, Wright Elizabeth, Cooper Glinda S, McAlindon Timothy E, Costenbader Karen H, Massarotti Elena M, Fitzgerald Lisa M, Jajoo Ramina, Husni M Elaine, Fossel Anne H, Pankey Helen, Ding Wei-Zi, Knorr Robert, Condon Suzanne, Fraser Patricia A

Abstract excerpt

OBJECTIVE: The high prevalence of systemic lupus erythematosus (SLE) among African American women may be due to environmental exposures, genetic factors, or a combination of factors. Our goal was to assess association of residential proximity to hazardous waste sites and genetic variation in 3 glutathione Stransferase (GST) genes (GSTM1, GSTT1, and GSTP1) with age at diagnosis of SLE. METHODS: Residential...

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PMID: 17195228
DOI: 10.1002/art.22308

Genes

GSTM1
GSTP1
GSTT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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