Article
Multiclonal asymptomatic Plasmodium falciparum infections predict a reduced risk of malaria disease in a Tanzanian population.
Microbes and infection - 1 Jan 2007
Bereczky Sándor, Liljander Anne, Rooth Ingegerd, Faraja Lea, Granath Fredrik, Montgomery Scott M, Färnert Anna
Abstract excerpt
Protective immunity to malaria is acquired after repeated exposure to the polymorphic Plasmodium falciparum parasite. Whether the number of concurrent antigenically diverse clones in asymptomatic infections predicts the risk of subsequent clinical malaria needs further understanding. We assessed the diversity of P. falciparum infections by merozoite surface protein 2 genotyping in a longitudinal population based...
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