Article
Complexity of Plasmodium falciparum infections is consistent over time and protects against clinical disease in Tanzanian children.
The Journal of infectious diseases - 1 Apr 1999
Färnert A, Rooth I, Svensson, Snounou G, Björkman A
Abstract excerpt
The complexity of Plasmodium falciparum populations in 21 children was studied in repetitive samples over 4 years in an area of Tanzania where the organism is holoendemic. Genotyping was done by a polymerase chain reaction method that targets three highly polymorphic regions of the merozoite surface protein (MSP) 1 block 2, MSP 2, and the glutamine-rich protein. Eight children were repeatedly parasitemic, 5 had...
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