Article
AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2007
Huang Yanchao, Laval Steven H, van Remoortere Alexandra, Baudier Jacques, Benaud Chriselle, Anderson Louise V B, Straub Volker, Deelder Andre, Frants Rune R, den Dunnen Johan T, Bushby Kate, van der Maarel Silvère M
Abstract excerpt
Mutations in dysferlin cause limb girdle muscular dystrophy 2B, Miyoshi myopathy and distal anterior compartment myopathy. Dysferlin is proposed to play a role in muscle membrane repair. To gain functional insight into the molecular mechanisms of dysferlin, we have searched for dysferlin-interacting proteins in skeletal muscle. By coimmunoprecipitation coupled with mass spectrometry, we demonstrate that AHNAK...
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