Article
Structural and functional genetic disorders of the great vessels and outflow tracts.
Annals of the New York Academy of Sciences - 1 Nov 2006
Bee Katharine J, Wilkes David, Devereux Richard B, Lerman Bruce B, Dietz Harry C, Basson Craig T
Abstract excerpt
Development of the aorta and pulmonary artery is a complex process involving multiple molecular genetic pathways that modulate morphogenesis of the outflow tracts and the anastomosis of branch vessels. Recent genetic studies of the cardiovascular system demonstrate that congenital and adult onset progressive disorders of the great vessels such as aneurysms are components of generalized vascular, cardiac, and...
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