Article
Genetic and Developmental Basis of Cardiovascular Malformations.
Clinics in perinatology - 1 Mar 2016
Azhar Mohamad, Ware Stephanie M
Abstract excerpt
Cardiovascular malformations (CVMs) are the most common birth defect, occurring in 1% to 5% of all live births. Genetic, epigenetic, and environmental factors all influence the development of CVMs, and an improved understanding of the causation of CVMs is a prerequisite for prevention. Cardiac development is a complex, multistep process of morphogenesis that is under genetic regulation. Although the genetic...
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