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Article

Modeling the therapeutic efficacy of p53 restoration in tumors.

Cell - 29 Dec 2006

Martins Carla P, Brown-Swigart Lamorna, Evan Gerard I

Abstract excerpt

Although restoration of p53 function is an attractive tumor-specific therapeutic strategy, it remains unclear whether p53 loss is required only for transition through early bottlenecks in tumorigenesis or also for maintenance of established tumors. To explore the efficacy of p53 reinstatement as...

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Identifiers

PMID: 17182091
DOI: 10.1016/j.cell.2006.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17182091-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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