Article
Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner.
FEBS letters - 9 Jan 2007
Kamei Yasutomi, Suganami Takayoshi, Kohda Takashi, Ishino Fumitoshi, Yasuda Kazuki, Miura Shinji, Ezaki Osamu, Ogawa Yoshihiro
Abstract excerpt
Paternally expressed 1 (Peg1)/mesoderm specific transcript (Mest) is an imprinted gene, which is only transcribed from the paternal (father's) allele. In some human cancer tissues, an alternatively spliced variant of PEG1/MEST mRNA using a different promoter of a distinct first exon is expressed from both paternal and maternal alleles. We previously reported that Peg1/Mest expression was markedly up-regulated in...
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