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Article

PINK1 mutation heterozygosity and the risk of Parkinson's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Jan 2007

Toft M, Myhre R, Pielsticker L, White L R, Aasly J O, Farrer M J

Abstract excerpt

BACKGROUND: Mutations in the PTEN-induced kinase 1 (PINK1) gene have been identified in recessively inherited and sporadic early-onset parkinsonism (EOP). METHODS: A total of 131 Norwegian patients diagnosed with Parkinson's disease were included. Of them, 89 participants had EOP (onset < or = 50 years); the remaining had familial late-onset disease (mean age at onset 64 years). PINK1 analysis included sequencing...

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Source

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Identifiers

PMID: 17172567
DOI: 10.1136/jnnp.2006.097840
PMCID: PMC2117782

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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