Carcinoembryonic antigen has a different molecular weight in normal colon and in cancer cells due to N-glycosylation differences.

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Article

Carcinoembryonic antigen has a different molecular weight in normal colon and in cancer cells due to N-glycosylation differences.

Cancer research - 15 Oct 1991

Garcia M, Seigner C, Bastid C, Choux R, Payan M J, Reggio H

Abstract excerpt

Carcinoembryonic antigen, an apical membrane glycoprotein expressed in normal human colonic epithelial cells, colonic polyps, tumor, and tissue culture cell lines originating from colonic adenocarcinomas, is generally considered to have a molecular weight of 180,000. Using sodium dodecyl sulfate-...

Topics

Carcinoembryonic Antigen
Colon
Colonic Neoplasms
Colonic Polyps
Electrophoresis, Polyacrylamide Gel
Epitopes
Glycosylation
Humans
Immunoblotting
Molecular Weight
Phenotype
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1717152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1717152-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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