Article
Genetic polymorphism of human glutamate oxaloacetate transaminase (GOT1) detected using isoelectric focusing and a sensitive and positive staining method.
International journal of legal medicine - 1 Jan 1991
Nakanaga M, Nadano D, Yasuda T, Tenjo E, Sawazaki K, Iida R, Fujiki N, Kishi K
Abstract excerpt
Genetic polymorphism of glutamate oxaloacetate transaminase (GOT1) was demonstrated in human erythrocytes by isoelectric focusing in thin layer polyacrylamide gels and a sensitive and positive detection method. Using this technique, five phenotypes, GOT1 1, 2, 2-1, 3-1 and 3-2 were determined and the estimated gene frequencies of GOT1*1, GOT1*2 and GOT1*3 in the Japanese population were 0.9740, 0.0173 and 0.0087,...
Topics
- Aspartate Aminotransferases
- Erythrocytes
- Gene Frequency
- Humans
- Isoelectric Focusing
- Japan
- Phenotype
- Polymorphism, Genetic
- Reference Values
- Staining and Labeling