Article
Ageing and the liver.
Acta gastro-enterologica Belgica - 1 Jan 2000
Sersté Thomas, Bourgeois Nadine
Abstract excerpt
Age does not spare the liver. We reviewed here the essential actual knowledge about age related modifications of this organ. Liver volume and blood flow decrease with age. Aging is also associated with a decline in the intrinsic metabolic activity of the hepatic parenchyma, and in the gene expression of proteins involved in intermediary metabolism, mitochondrial respiration and drug metabolism. Aged hepatocytes...
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