Article
Typing and subtyping of Clostridium difficile isolates by using multiple-locus variable-number tandem-repeat analysis.
Journal of clinical microbiology - 1 Mar 2007
van den Berg Renate J, Schaap Inge, Templeton Kate E, Klaassen Corné H W, Kuijper Ed J
Abstract excerpt
Using the genomic sequence of Clostridium difficile strain 630, we developed multiple-locus variable-number tandem-repeat analysis (MLVA) with automated fragment analysis and multicolored capillary electrophoresis as a typing method for C. difficile. All reference strains, representing 31 serogroups, 25 toxinotypes, and 7 known subtypes of PCR ribotype 001, could be discriminated from each other. Application of...
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