Article
Mycophenolate mofetil as an alternate immunosuppressor for autoimmune lymphoproliferative syndrome.
Journal of pediatric hematology/oncology - 1 Dec 2006
Kossiva Lydia, Theodoridou Maria, Mostrou Glykeria, Vrachnou Effie, Le Deist Francoise, Rieux-Laucat Frederick, Kanariou Maria G
Abstract excerpt
Autoimmune lymphoproliferative syndrome (ALPS) is a disorder due to a genetic defect concerning programmed cell death (apoptosis). Most patients are carriers of a heterozygous mutation affecting the TNFRSF6 (Fas). Treatment of autoimmune complications of ALPS includes corticosteroids, gamma-globu...
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