Article
Incidence of Crohn's disease and CARD15 mutation in a small township in Sicily.
European journal of epidemiology - 1 Jan 2006
Cottone M, Renda M C, Mattaliano A, Oliva L, Fries W, Criscuoli V, Modesto I, Scimeca D, Maggio A, Casà A, Maisano S, Mocciaro F, Sferrazza A, Orlando A
Abstract excerpt
BACKGROUND: The incidence of Crohn's disease (CD) has been shown to be lower in Southern than in Northern Europe. Data on the frequency of the NOD2/CARD15 mutations for Mediterranean area are very scant. AIM: To determine the incidence of CD from 1979 to 2002 in a township in Sicily together with the allele frequency of NOD2/CARD15 mutations in patients, family members and controls, and to determine the allele...
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