Article
Differential regulation of twitching motility and elastase production by Vfr in Pseudomonas aeruginosa.
Journal of bacteriology - 1 Jul 2002
Beatson Scott A, Whitchurch Cynthia B, Sargent Jennifer L, Levesque Roger C, Mattick John S
Abstract excerpt
Vfr, a homolog of Escherichia coli cyclic AMP (cAMP) receptor protein, has been shown to regulate quorum sensing, exotoxin A production, and regA transcription in Pseudomonas aeruginosa. We identified a twitching motility-defective mutant that carries a transposon insertion in vfr and confirmed that vfr is required for twitching motility by construction of an independent allelic deletion-replacement mutant of vfr...
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