Article
Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15.
Human reproduction (Oxford, England) - 1 Mar 2007
Zondervan Krina T, Treloar Susan A, Lin Jianghai, Weeks Daniel E, Nyholt Dale R, Mangion Jon, MacKay Ian J, Cardon Lon R, Martin Nicholas G, Kennedy Stephen H, Montgomery Grant W
Abstract excerpt
BACKGROUND: Endometriosis is a common disease with a heritable component. The collaborative International Endogene Study consists of two data sets (Oxford and Australia) comprising 1176 families with multiple affected. The aim was to investigate whether the apparent concentration of cases in a proportion of families could be explained by one or more rare variants with (near-)Mendelian autosomal inheritance....
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