Article
Characterization of the Interactome of the Human MutL Homologues MLH1, PMS1, and PMS2
6 Dec 2006
Abstract excerpt
Postreplicative mismatch repair (MMR) involves the concerted action of at least 20 polypeptides. Although the minimal human MMR system has recently been reconstituted in vitro, genetic evidence from different eukaryotic organisms suggests that some steps of the MMR process may be carried out by more than one protein. Moreover, MMR proteins are involved also in other pathways of DNA metabolism, but their exact...
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