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Article

Myopathy associated with anti-signal recognition peptide antibodies: clinical heterogeneity contrasts with stereotyped histopathology.

Muscle & nerve - 1 Mar 2007

Dimitri Dalia, Andre Chantal, Roucoules Jacques, Hosseini Hassan, Humbel René-Louis, Authier François-Jérôme

Abstract excerpt

We report three patients with anti-signal recognition particle antibodies who had different presenting clinical pictures, mimicking acute polymyositis, limb-girdle muscular dystrophy, and acute rhabdomyolysis. Muscle biopsies typically showed necrotizing myopathy with little or no inflammation and deposits of membrane attack complex (C5b-9) in endomysial capillaries. The clinical course was severe in two patients...

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Source

Identifiers

PMID: 17143889
DOI: 10.1002/mus.20693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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