Article
Do high incidences of common neoplasms depend on evolutionary abandoned regulatory loops revived in tumor cells by mutations?
Medical hypotheses - 1 Jan 2007
Kurbel Sven
Abstract excerpt
Neoplasms seem much more common than one might expect, considering complexity of the required cell malfunctions. It seems very unlikely to get them all set in the single cell by pure chance. Here presented idea is neoplasms exploit evolutionary abandoned regulatory mechanisms still contained in our genome. During evolution numerous changes have occurred in cell biology of multicellular organisms. Regulatory...
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