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Article

Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation.

International journal of cancer - 1 Mar 2007

Vangsted Annette, Gimsing Peter, Klausen Tobias W, Nexø Bjørn A, Wallin Håkan, Andersen Pernille, Hokland Peter, Lillevang Søren T, Vogel Ulla

Abstract excerpt

Individual variations in the ability to cope with DNA damage by DNA repair may be essential for the response to chemotherapy, since cancer cells from patients with an effective DNA repair may survive treatment. We have studied the effect on time to treatment failure (TTF) and overall survival (OS) of polymorphism in the DNA repair genes ERCC1, ERCC2 and XRCC3, and in the apoptotic genes PPP1R13L and CD3EAP in 348...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17131345
DOI: 10.1002/ijc.22411

Genes

ERCC2
XRCC3
ERCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation.PMID 17131345Read ↗

DNA repair genes polymorphisms in multiple myeloma: no association with XRCC1 (Arg399Gln) polymorphism, but the XRCC4 (VNTR in intron 3 and G-1394T) and XPD (Lys751Gln) polymorphisms is associated with the disease in Turkish patients.Semantic proximity Read ↗

Variation in DNA repair genes XRCC3, XRCC4, XRCC5 and susceptibility to myeloma.Semantic proximity Read ↗

Impact on response and survival of DNA repair single nucleotide polymorphisms in relapsed or refractory multiple myeloma patients treated with thalidomide.Semantic proximity Read ↗

Genetic variants in DNA repair pathways are not associated with disease progression among multiple myeloma patients.Semantic proximity Read ↗

Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation.Semantic proximity Read ↗

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