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Article

Is HLA class II profile relevant for the study of large-scale differentially expressed genes in type 1 diabetes mellitus patients?

Annals of the New York Academy of Sciences - 1 Oct 2006

Rassi Diane M, Junta Cristina M, Fachin Ana L, Sandrin-Garcia Paula, Mello Stephano S, Fernandes Ana P M, Deghaide Neife N H S, Foss-Freitas Maria C, Foss Milton C, Sakamoto-Hojo Elza T, Passos Geraldo A S, Donadi Eduardo A

Abstract excerpt

We have previously identified 30 differentially expressed genes when comparing recently diagnosed type 1 diabetes mellitus (DM-1) patients and controls paired for sex, age, and ethnic background. In this article we performed the hierarchical clustering of these genes taking into account the human-leukocyte-antigen (HLA)-DRB1/DQB1 profile. The dendrogram obtained using the Cluster program grouped patients and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17130570
DOI: 10.1196/annals.1375.046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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