Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prenatal screening for chromosome abnormalities using maternal serum chorionic gonadotrophin, alpha‐fetoprotein, and age

1 Feb 1991

Abstract excerpt

Human chorionic gonadotrophin (hCG) levels were assayed retrospectively in stored maternal serum samples from 78 chromosomally abnormal pregnancies and 410 controls matched for gestation and maternal age. The median serum hCG concentration in 49 pregnancies with Down's syndrome was significantly elevated, at 2.18 multiples of the normal median. Significantly reduced hCG concentrations were found in a group of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prenatal Screening and Diagnostics

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1712100
DOI: 10.1002/pd.1970110204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prenatal screening for chromosome abnormalities using maternal serum chorionic gonadotrophin, alpha‐fetoprotein, and agePMID 1712100Read ↗

Prenatal Screening for Down's Syndrome with Use of Maternal Serum MarkersSemantic proximity Read ↗

Screening of Maternal Serum for Fetal Down's Syndrome in the First TrimesterSemantic proximity Read ↗

MATERNAL SERUM SCREENING FOR FETAL DOWN SYNDROME IN IVF PREGNANCIESSemantic proximity Read ↗

First‐trimester biochemical screening for fetal chromosome abnormalities and neural tube defectsSemantic proximity Read ↗

First‐trimester free beta (hCG) screening for Down syndromeSemantic proximity Read ↗

Down's syndrome screening in multiple pregnancies using alpha‐fetoprotein and free beta hCGSemantic proximity Read ↗

Prospective intervention trial of a screening protocol to identify fetal trisomy 18 using maternal serum alpha‐fetoprotein, unconjugated oestriol, and human chorionic gonadotropinSemantic proximity Read ↗

Dimeric Inhibin A as a Marker for Down's Syndrome in Early PregnancySemantic proximity Read ↗

COMBINING INHIBIN A WITH EXISTING SECOND-TRIMESTER MARKERS IN MATERNAL SERUM SCREENING FOR DOWN'S SYNDROMESemantic proximity Read ↗

Second-trimester prenatal screening for Down syndrome and the relationship of maternal serum biochemical markers to pregnancy complications with adverse outcomeSemantic proximity Read ↗

Predictive value of the triple screening test for the phenotype of Down syndrome.Semantic proximity Read ↗

DOWN'S SYNDROME SCREENING MARKER LEVELS FOLLOWING ASSISTED REPRODUCTIONSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.