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Article

Predictive value of the triple screening test for the phenotype of Down syndrome.

American journal of medical genetics - 16 Jul 1999

Tanski S, Rosengren S S, Benn P A

Abstract excerpt

Maternal serum alpha-fetoprotein (MSAFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) are routinely measured in the second trimester ("triple" test) and combined with maternal age to evaluate risk for fetal Down syndrome. Triple test results and clinical findings were retrospectively reviewed for 30 newborns with Down syndrome to determine whether analyte values or second trimester risks...

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Source

Identifiers

PMID: 10406664
DOI: 10.1002/(sici)1096-8628(19990716)85:2<123::aid-ajmg5>3.0.co;2-m

Genes

AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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