Article
Expression and significance of leukocyte membrane cofactor protein transcript in systemic lupus erythematosus.
Lupus - 1 Apr 2012
Biswas B, Kumar U, Das N
Abstract excerpt
Membrane cofactor protein (MCP) is a complement regulatory protein ubiquitously expressed on most nucleated cells. Since MCP protects autologous cells from complement-mediated injury, it is suggested to have a protective role against the self-tissue damage in inflammatory conditions such as systemic lupus erythematosus (SLE). However, the relevance of MCP in human SLE is not well explored. To assess the...
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