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Article

Cystic fibrosis gene expression is not correlated with rectifying Cl- channels.

15 Jun 1991

Abstract excerpt

Cystic fibrosis (CF) involves a profound reduction of Cl- permeability in several exocrine tissues. A distinctive, outwardly rectifying, depolarization-induced Cl- channel (ORDIC channel) has been proposed to account for the Cl- conductance that is defective in CF. The recently identified CF gene is predicted to code for a 1480-amino acid integral membrane protein termed the CF transmembrane conductance regulator...

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Share to Advanced biosensing and bioanalysis techniques
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Identifiers

PMID: 1711224
DOI: 10.1073/pnas.88.12.5277

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Source receipt: pubmed, retrieved 7 Sept 2026.

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