Article
Partial complementation of the UV sensitivity of Deinococcus radiodurans excision repair mutants by the cloned denV gene of bacteriophage T4.
Mutation research - 1 May 1991
Gutman P D, Yao H L, Minton K W
Abstract excerpt
Deinococcus radiodurans has 2 endonucleases that incise UV-irradiated DNA. UV endonuclease-alpha and UV endonuclease-beta, that are believed to functionally overlap. Both endonucleases must be mutationally inactivated to yield an incisionless, markedly UV-sensitive phenotype. denV, the bacterioph...
Topics
- Chromosomes
- Cloning, Molecular
- DNA Glycosylases
- DNA Repair
- Gene Expression
- Genes, Viral
- Genetic Complementation Test
- Gram-Positive Bacteria
- Mutation
- N-Glycosyl Hydrolases
- T-Phages
- Transformation, Genetic
