Article
The protein kinase TOUSLED is required for maintenance of transcriptional gene silencing in Arabidopsis.
EMBO reports - 1 Jan 2007
Wang Yu, Liu Jun, Xia Ran, Wang Junguo, Shen Jie, Cao Rui, Hong Xuhui, Zhu Jian-Kang, Gong Zhizhong
Abstract excerpt
TOUSLED-like kinases (TLKs) are highly conserved in plants and animals, but direct evidence linking TLKs and transcriptional gene silencing is lacking. We isolated two new alleles of TOUSLED (TSL). Mutations of TSL in ros1 reactivate the transcriptionally silent 35S-NPTII transgene and the transcriptionally silent endogenous loci TSI (TRANSCRIPTIONAL SILENCING INFORMATION). Chromatin immunoprecipitation (ChIP)...
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