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Article

In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphisms.

Pharmacogenetics and genomics - 1 Dec 2006

Schaefer Melanie, Roots Ivar, Gerloff Thomas

Abstract excerpt

BACKGROUND: Genetic variation of the human ABCB1 (P-glycoprotein; MDR1 gene product) efflux transporter is strongly suggested as a determinant factor governing the pharmacokinetics of diverse drugs and xenobiotics. Despite various efforts to associate polymorphisms in ABCB1 to actual clinical effect and transport function, information is still inconsistent or even controversial. METHODS AND RESULTS: Using...

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Source

Identifiers

PMID: 17108809
DOI: 10.1097/01.fpc.0000230113.03710.34

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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